Resistin- and Obesity-associated Metabolic Diseases
نویسندگان
چکیده
منابع مشابه
Resistin- and Obesity-associated metabolic diseases.
The link between obesity and diabetes is strong as well as complex. Fat cells produce many circulating regulators of insulin sensitivity, including pro-inflammatory cytokines. In rodents, resistin is produced by adipose tissue, and is a significant regulator of glucose metabolism and insulin sensitivity. In humans, resistin is derived made mainly from macrophages. Given the emerging interrelati...
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Obesity is a major risk factor for insulin resistance and type 2 diabetes mellitus. Adipocytes secrete numerous substances that might contribute to peripheral insulin sensitivity. These include leptin, tumor necrosis factor alpha, Acrp30/adiponectin/adipoQ and interleukin 6, the potential roles of which are briefly reviewed here. Thiazolidinedione (TZD) antidiabetic drugs regulate gene transcri...
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ژورنال
عنوان ژورنال: Hormone and Metabolic Research
سال: 2007
ISSN: 0018-5043,1439-4286
DOI: 10.1055/s-2007-985897